Bioss Inc.'s TPX2 Monoclonal Antibody is a Mouse monoclonal antibody. The TPX2 Monoclonal Antibody was generated using TPX2, and TPX2 microtubule nucleation factor as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Western Blot.
Description
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation